Sep 01, 2004 · This study was conducted to develop an emulgel formulation of chlorphenesin (CHL) using 2 types of gelling agents: hydroxypropylmethyl cellulose (HPMC) and Carbopol 934. The influence of the type of the gelling agent and the concentration of both the oil phase and emulsifying agent on the drug ... gel formulation is given in Table 1. Evaluation of gel formulations Evaluation parameters of gel formulations are given in Table 2 and they are: pH The pH value of polyherbal gel formulation was determined by using a pH meter. The measurement was performed at 1, 30, 60, 90 days gated and emulgel was optimized using 23 factori-al design. The developed emulgel were efficacious for the delivery of lipophilic and poorly soluble drugs such as Etodolac. Thus results demonstrate the formulation were stable and showed improved permeation of the drug from the emulgel com-pared to other emulgel formulations.
The aim of the present research work is to decrease the systemic side effects and to create a more pronounced effect of Nano emulgel of Adapalene with lower doses of the drug. Nano Emulgel emerged as one of the most interesting topical drug delivery
the other formulations [3, 4]. HEC formulation was developed and in vitro transdermal penetration of this formulation was compared with that commercial Vurdon gel 1% - Help. The objective of present study was conducted to develop a topical gel formulation of diclofenac sodium using HEC polymer. The gels were May 24, 2016 · Formulation development of emulgel 6. Optimization of emulgel 21. 7. Evaluation of Emulgel Appearance pH Viscosity Drug content Spreadability Swelling Index In- vitro diffusion study Ex- vivo diffusion study Skin irritation study Ex -vivo bioadhesive strength Stability study 8. Data Analysis 9. Introduction: Topical drug administration is simplest and easiest route of localized drug delivery anywhere in the body by routes as ophthalmic, rectal, vaginal and skin. FORMULATION DEVELOPMENT AND EVALUATION OF DICLOFENAC SODIUM GEL USING WATER SOLUBLE POLYACRYLAMIDE POLYMER U. D. SHIVHARE*, K. B. JAIN, V. B. MATHUR, K. P. BHUSARI, A. A. ROY Sharad, Pawar College of Pharmacy, Wanadongri, Hingna Road, Nagpur-441110, India High molecular weights water soluble homopolymer of acrylamide are reported to possess
Formulation and Evaluation of Herbal Emulgel of Pothos scandens Linn for Burn Wound Healing Activity Mohammed Haneefa K.P1*, Abid2, Shahima Hanan K3, Guru Prasad Mohanta4,Chandini Nayar5 1, 2, 3 Alshifa College of Pharmacy, Poonthavanam Post, Kerala, India *Research Scholar,School of Chemical & Biotechnology, SASTRA University, Tamil Nadu, India formulation of stable systems by reducing interfacial and surfacial tension thereby increasing the viscosity of the liquid phase . In this way the circuit of gelling administrators into water stage changes over the emulsion into stable emulgel formulation [4,5]. Emulgels are nothing but emulsions that may be of water-in-oil Formulation and evaluation of Cyclosporin A emulgel for ocular delivery Yan Shen1, Xiang Ling1, Weiwei Jiang2, Shuang Du1, Yang Lu3, and Jiasheng Tu1 1Department of Pharmaceutics, China Pharmaceutical University, Nanjing, China, 2Patent Examination Cooperation Center of SIPO, Jiangsu,
The aim of the following research was to formulate benzyl benzoate in emulgel form and to evaluate the release of the medicament from it. Emulgel containing 25% w/w of benzyl benzoate was prepared by addition of a gelling agent; Carbopol 934 to an emulsion using Span 80 as emulsifying agent. The tested formulations can be arranged in the following descending order according to the release of benzyl benzoate from them : emulgel containing 20 gm of Carpobol 934 > emulgel containing 10 gm of Carpobol 934 >lotion>gel> ointment. IV. Discussion The drug content of Clotrimazole emulgel was measured by dissolving a known weight of the emulgel formulation (one gram) in 100 ml methanol, appropriate dilutions were made and the resulting solution was then filtering using millipore filter (0.45 µm). Absorbance was emulgel formulations that includes gelling agents from different groups: natural, synthetic and semi-synthetic. The first step of semisolid drugs development is a selection of appropriate base, thru the large range of bases an emulgel is one of most prefered. In case of pharmaceutical forms, emulgels are emulsions
The tested formulations can be arranged in the following descending order according to the release of benzyl benzoate from them : emulgel containing 20 gm of Carpobol 934 > emulgel containing 10 gm of Carpobol 934 >lotion>gel> ointment. IV. Discussion May 29, 2019 · The present study aims at preparing an Emulgel formulation of Meloxicam using emulsifiers and various gelling agents along with the use of. PDF | Emulgel is one of the recent technologies in NDDS used for dual control release of emulsion and gel for topical use. PDF | Emulgel is one of the recent technologies in NDDS used for dual control release of emulsion and gel for topical use. ... Formulation & Evaluation of Aceclofenac Emulgel. ... dissolution ... Stability studies indicated that the formulation remained unaffected at accelerated storage conditions. Conclusion: Results indicated that the micro-emulgel has potential for sustained action of drug release and may act as a promising tool to enhancepercutaneous delivery of etoricoxib.
4.10 Stability Studies: The optimized emulgel formulation was selected for stability study. Sufficient quantity of emulgel formulation was sealed in 10 gm collapsible tube in triplicate, and subjected to stability studies at 5°C, 25°C,/60%RH, 30°C 65%RH and 40°C/ 75%RH for a period of 3 months. 4.10 Stability Studies: The optimized emulgel formulation was selected for stability study. Sufficient quantity of emulgel formulation was sealed in 10 gm collapsible tube in triplicate, and subjected to stability studies at 5°C, 25°C,/60%RH, 30°C 65%RH and 40°C/ 75%RH for a period of 3 months. d emulgel formulations. Selection of a suitable release model was based on the values of R2 (correlation coefficient), k (release constant) obtained from the curve fitting of release data. It was found that all the formulations follows the zero order kinetics. The optimized formulation F7 showed a shear thinning